|
|
|
|
|
|
- Formulation makes water soluble cannabidiol (CBD) up to 40x better absorbed
- Applies to fat-soluble medications and foods, including curcumin and Vitamin D |
PERTH, W AUSTRALIA, Dec 13, 2019 - (ACN Newswire) - Holista CollTech (ASX: HCT, Holista) announced that it has filed its 100%-owned global patent for platform technology that will deliver many fat-soluble medications by creating a water-soluble delivery system. This patented process can apply to a whole range of molecules including the Cannabidiol (CBD) oil industry.
The commercial benefits for the CBD producers include making their CBD formulation up to 40 times more potent (allowing them to reduce their dosages significantly) as well as making their product palatable for the young and the elderly.
Fat-soluble molecules have poor bioavailability as they don't dissolve well and reach the bloodstream. As such, a higher dosage needs to be ingested. This is both wasteful and costly. The platform technology will particularly benefit the Cannabidiol (CBD) oil industry where the active material is scarce, costly and poorly water-soluble.
In a statement released this week, by our Project Leader and head of Holista's Technical Advisory Panel, Dr Roscoe Moore Jr stated "Working on developing this technology is exciting. Most medicine consumed orally is wasted due to its poor absorption by the body. This is especially true for CBD, which is also expensive. More important, the integrity of the final molecule is preserved exactly as it is found in nature and hence, there is no apparent need for any lengthy approvals process anywhere in the world. We only use materials certified as 'Generally Regarded as Safe' (GRAS) by the FDA[1]."
Dr Moore is the retired Assistant Surgeon General of the United States. An advocate of evidenced based CBD, he currently sits on several Company boards linked to CBD in the United States and Canada.
CBD Oil has an earthy, musky and lingering bitter taste due to the high concentration of organic compounds that make it very unpalatable. This makes formulating CBD for oral consumption difficult. The taste masking technology linked to this patented formulation used GRAS botanicals to allow wider applications in pharmaceutical and food with oral dosing.
"Holista drew from parallel work done on the turmeric molecule which is also very fat soluble" said Dr Swanand Malode, leader the teams in Europe and Asia that worked on this technology for more than five years.
"We note that there is growing consensus in the medical community that CBD can be used to improve patient outcomes for conditions such as seizure, inflammation, pain, psychosis or mental disorders, inflammatory bowel disease, nausea, migraines, depression, anxiety" said Dr Rajen Manicka, CEO of Holista.
Holista is focused on fat-soluble substances such as CBD, curcumin and Vitamin D, targeting initially the food and nutraceutical markets in Australia and North America.
According to a new estimate from cannabis industry analysts the Brightfield Group[2], the hemp-CBD market alone could hit $22 billion by 2022. The prospects for Australia are also increasing. According to a 2016 University of Sydney report[3], "Medicinal Cannabis in Australia: Science, Regulation & Industry", found that the Australian medicinal cannabis market, if it emulates cannabis regulations in Netherlands and Canada, may produce demand for as much as 8,000 kg of product. Australia approved medical cannabis in 2016 and is working towards liberalising this space further.
CBD, a non-psychoactive cannabinoid found in cannabis, has had a surge in popularity. Unlike Tetrahydrocannabinol (THC) the chemical compound that gives cannabis its psychoactive effects, CBD has been shown to help patients with Post Traumatic Stress Disorder (PTSD), anxiety, Multiple Sclerosis and epilepsy - without having the harmful effects.
The patent was registered in the USA and filed for a global coverage, as US Filing No: 16/694,197 (the patent may be viewed on the Holista website). Holista has instructed its patenting firm to secure all global strategic markets world-wide.
With the patent filing completed, Holista has commenced negotiations with companies involved in CBD processing in North America and expect these negotiations to complete in 2020, leveraging the expertise and network of Dr Moore Jr.
The commercial model will seek to charge an industry-standard formulation fee for non-exclusive access and then a quarterly licensing fee and royalty based on wholesale pricing of the licensee product.
[1] FDA - Food and Drug Administration, USA
[2] For more information on the Brightfield Group, refer to www.brightfieldgroup.com
[3] Details at mgcpharma.com.au/wp-content/uploads/2016/03/mgc_whitepaper_final-sml.pdf
Contact:
Corporate Affairs & Business Opportunities
Dr Rajen Manicka: rajen.m@holistaco.com
General Enquiries: enquiries@holistaco.com
Media and Investor Relations:
WeR1 Consultants Pte Ltd
P: +65 67374844; E: holista@wer1.net
About Holista
Holista CollTech Ltd (ASX: HCT) is a research-driven biotech company, the result of a merger between Holista Biotech Sdn Bhd and CollTech Australia Ltd. Headquartered in Perth and with extensive operations in Malaysia, the company is dedicated to delivering first-class natural ingredients and wellness products globally. Holista is a leader in the research of herbs and ingredients for the making of healthier food. Holista's suite of ingredients, among other things, includes low-GI baked products, reduced-sodium salts, low-fat fried foods and low calories sugar without compromising taste, odour and mouthfeel. Holista remains the only company to produce sheep (ovine) collagen using patented extraction methods. For more information, http://www.holistaco.com.
Topic: Press release summary
Source: Holista CollTech Ltd
Sectors: Healthcare & Pharm, Cannabis
https://www.acnnewswire.com
From the Asia Corporate News Network
Copyright © 2024 ACN Newswire. All rights reserved. A division of Asia Corporate News Network.
|
|
|
|
|
|
|
| |
| Holista CollTech Ltd Related News |
|
| Oct 12, 2021 17:00 HKT/SGT |
| Berjaya Partners Holista to Offer Healthy Breads and Foods in Starbucks Malaysia, 7-Eleven and Other F&B Outlets |
|
| June 18, 2021 14:00 HKT/SGT |
| Malaysia Permission Granted for COVID-19 Test Kit from China for Emergency Use; Homegrown Holista Colltech Receives Initial Order for 15,000 Units for Deployment |
|
| June 18, 2021 14:00 HKT/SGT |
| 马来西亚允许了来自中国的新冠肺炎测试剂盒以供为紧急使用；Holista Colltech 收到 15,000 单位的初始订单 |
|
| June 18, 2021 14:00 HKT/SGT |
| Malaysia Diberikan Kebenaran Untuk Kit Uji COVID-19 dari China Bagi Tujuan Penggunaan Kecemasan; Syarikat Tempatan Holista Colltech Menerima Pesanan Awal Sebanyak 15,000 Unit Untuk Penggunaan |
|
| June 18, 2021 14:00 HKT/SGT |
| 馬來西亞允許了來自中國的新冠肺炎測試劑盒以供為緊急使用；Holista Colltech 收到 15,000 單位的初始訂單 |
|
| More news >> |
|
|
|
